Meet Some of the Physicians
and Cervical Spinal Cord
Injury Patients in the
AST-OPC1 Clinical Trial
 

Careers at Asterias Biotherapeutics

Asterias Biotherapeutics is a growing and dynamic biotechnology company focusing in the cutting edge field of regenerative medicine. We are committed to treat diseases where existing therapies do too little or do not exist at all. Both our corporate center and R&D facilities are co-located in the San Francisco Bay Area, one of the hottest regions for biopharma in the U.S. Our active development programs evolve continuously, so we are always looking for high caliber talent with biotech experience to join our team. Asterias offers competitive salaries with comprehensive benefits.

Please explore available opportunities to join our team in current job postings below:

  •   
    Senior Scientist, Immunology
    Full Time
    Fremont, CA

    Title: Senior Scientist, Immunology

    Department: Product Development

    Reports to: Executive Director, Product Development

    Position Description:

    Asterias Biotherapeutics is seeking a talented and dynamic scientist for a Senior Scientist position in the Regenerative Medicine and Immune-oncology Product Development team. This individual will be directly responsible for executing experiments and leading ongoing efforts in the discovery and development of novel stem cell therapies for advancement into the clinic. The position will actively support projects both in early and late stage development across multidisciplinary teams.

    Summary of Essential Job Functions:

    • Drive discovery and translational efforts to support projects aimed at optimizing the differentiation of human pluripotent stem cells into desired cell types
    • Manage and identify key external collaborations that would enhance decisions on projects and/or yield new target indications
    • Lead efforts for development of in vitro cell-based assays to characterize the phenotype and potency of candidate cell therapies
    • Contribute to the hands-on development and performance of immune-monitoring assays for patients receiving candidate cell therapies
    • Apply knowledge and know-how internally on project teams as well as represent the company externally
    • Lead identification and testing of novel scientific /technical opportunities
    • Design and execute experimental plans, provide interpretation, troubleshoot and suggest next steps
    • Maintain laboratory notebooks in a professional, and accurate manner
    • Interact and collaborate with members of all other departments at Asterias, including Analytical Technologies, Process Development, and Clinical Operations
    • Prepare study reports and presentations for group meetings, conferences, publications and regulatory filings

    Minimum Requirements

    • Ph.D. degree with 5 or more years post-graduate experience related to the field of immune-oncology and stem cell biology
    • Preference will be given to candidates with a strong background in T cell immunology and dendritic cell biology
    • Proven record of applicable immunology or immune-oncology relevant publications
    • Proficient cell culture techniques of human cell lines, pluripotent stem cells, and primary cells
    • Hands-on experience with isolating, culturing, and expanding antigen-specific lymphocytes from human whole blood
    • Immunological techniques (Multi-color flow cytometry, ELISpot, and ELISA), Cell-based immunoassays (MLR, CTL assays)
    • Basic molecular biology techniques (DNA/RNA preparation, qPCR, cloning)
    • Requires up to 5-10% international travel
    • Computer skills in Excel, PowerPoint, word processing, and data presentation
    • Excellent organizational, communication, and written skills

    Disclaimer:

    The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed.

    Please send your resume to our hiring department (cover letter optional) email jobs@asteriasbio.com

    Apply using webmail: Gmail / AOL / Yahoo / Outlook

  •   
    Materials Management Specialist
    Full Time
    Fremont, CA

    Title: Materials Management Specialist

    Department: Manufacturing

    Reports to: Director, Technical Operations

    Position Description:

    The Materials Management Specialist will be responsible for material procurement, warehousing, inventory management of cGMP materials, and for performing shipping and receiving of non-GMP/GMP materials.

    Responsibilities:

    • Receive, inspect, disinfect, warehouse, and distribute cGMP raw materials, components, intermediates, and final drug product material while following SOPs.
    • Maintain inventory by identifying, labeling, and placing materials and supplies in stock; recording location of inventory and cycle counts.
    • Locate materials and supplies by pulling and verifying materials and supplies listed on production orders.
    • Perform material transfers into and from the manufacturing facility including dispensing, staging materials, performing material wipe down, receiving intermediates, receiving finished goods and returning materials to inventory.
    • Document materials and supplies disposition by recording units delivered and location of units.
    • Adhere to all safety procedures and GMP requirements at all times.
    • Keep warehouse operation clean and inspection ready at all times.

    Requirements

    • High school diploma.
    • 2+ years of experience in shipping, receiving, and warehousing operations preferably in a scientific or chemistry-based GMP manufacturing environment.
    • Meticulous attention to detail including the ability to maintain timely, accurate and legible documentation is required.
    • A positive attitude, the ability to work collaboratively with a wide range of customers and a commitment to providing excellent service is required.
    • Excellent multi-tasking and organizational skills.
    • Ability to lift 50Lb and to work while standing and walking is required.
    • Good computer skills including: MS Word, Excel.
    • Ability to work under pressure and tight time-lines, and effectively communicate to internal stakeholders and external partners.
    •  

    Disclaimer:

    The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed.

    Please send your resume to our hiring department (cover letter optional) email jobs@asteriasbio.com

    Apply using webmail: Gmail / AOL / Yahoo / Outlook

  •   
    Manufacturing Associate
    Full Time
    Fremont, CA

    Title: Manufacturing Associate

    Department: Manufacturing

    Reports to: Director, Technical Operations

    Position Description:

    We are seeking a highly motivated Manufacturing Associate with experience in cGMP manufacturing and cell culture. This individual will perform a variety of procedures in a manufacturing environment in compliance with cGMP regulations to manufacture cell therapy products for use in human clinical trials.

    Responsibilities:

    • Produce cell therapy products using undifferentiated human embryonic stem cells in accordance with the manufacturing procedures, SOPs, and approved protocols in cGMP manufacturing environment
    • Prepare required reagents, solutions, and buffers according to SOPs and approved protocols
    • Maintains aseptic clean room environments to comply with current Good Manufacturing Practices (cGMPs) and Standard Operating Procedures (SOPs)
    • Keeps detailed documentation in compliance with SOPs and Good Documentation Practice
    • Operate and maintain cell culture laboratory equipment for production; e.g. Biosafety cabinets, incubators, centrifuges etc.
    • Maintain supplies and reagents inventories, and order as needed
    • Write and/or revise SOPs, protocols, reports, and other required documentation
    • Provide support for commissioning and validation activities in addition to other facility start-up activities, as needed
    • Collaborate with cross-functional teams i.e., Quality, Facilities, Product Development, and Analytical Technologies
    • Perform additional job related duties as required

    Requirements

    • Bachelor/Associate Degree in Biology/Chemistry/Life Sciences or related field, or Biotech certificate.
    • 2+ years relevant cGMP manufacturing experience in Pharmaceutical/Biotech industry is preferred
    • Aseptic manufacturing experience is highly desired
    • Mammalian cell culture experience is preferred
    • Experience writing standard operating procedures and other cGMP documentation is preferred
    • Experience writing investigation, deviation and change control documentation is preferred
    • Ability to understand, apply, and evaluate basic biology and scientific principles as appropriate for the position
    • Excellent organizational and multi-tasking skills, attention to detail, and the ability to adapt to changing priorities
    • Ability to identify and elevate processing issues and support solutions
    • Must be able to work weekends and holidays as required
    • Excellent oral and written communications skills and a collegial personality
    • Thrives and succeeds in a team-oriented environment
    • Computer literacy including fluency with Microsoft Word, Excel, Outlook
    • Participate at appropriate department meetings
    • Ability to sit or stand for long periods of time, and ability to lift 25-30 lbs

    Disclaimer:

    The above statements are intended to describe the general nature and level of work being performed by people assigned to this classification. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed.

    Please send your resume to our hiring department (cover letter optional) email jobs@asteriasbio.com

    Apply using webmail: Gmail / AOL / Yahoo / Outlook

Asterias Biotherapeutics Tel: (510) 456-3800